The room has exquisite bones: the windows, flooring and decorative crown molding. If simplicity is what you want but with a bit more personal taste, I suggest the following:

1) paint the walls white that has a soft, warm undertone such as Benjamin and Moore's moonlight white or Dove. (Or try any good paint store for help on picking the right white color.) Paint the molding a stark white with an egg shell or gloss finish.

2) keep the bed covering as is. I love the warm colors and mixed patterns. If you do want more comfort, yes add a thicker mattress. Can you get a fabric similar for the table top? Or just remove the fabric from the table top, painting or stenciling it with a similar pattern. (see #5 below for where to look for stencils.)

3) Move the table to the head of the bed, add a modern lamp and lots of books or other meaningful, personal items.

4) Add a comfy chair or as suggested above, pile lush floor pillows where the table is, under the window. Use complementing or solid color fabric on the floor pillows or chair. Add a small table with more lighting. (See my most popular post on Floor Pillows. Towards the end you will see examples of suitable floor pillows. Or just do a search here on Houzz and the internet.)

5) Make a dramatic statement above the bed with a very large painting. Select with care based upon your personal taste: abstract, minimal but with a hint or some of the colors found in the bedding fabric. It doesn't have to be centered, a little off centered will do since there appears to already be something on the wall above the bed. Do add a soft art lamp above the painting. (If you don't have money for the painting, purchase a very large canvas, take your time and create it yourself (collage it, play around with paint on paper before adding it to your canvas, stencil it, etc.--but have fun and make it personal) Here's a great place for getting a wide range of designs for stenciling: Cutting Edge Stencils. Note you don't have to take the design all the way to the edge of the canvas!

6) Add a small (wool) flokati rug in front of the bed. Get the kind that comes from Greece, it has long-fibers and a plush pile. These rugs are to die for when it comes to comfort and texture--and they're inexpensive. Take a look and if you like it, be sure to get wool: Flokati Rug.Net.

These ideas will give you lots of varying textures to get rid of the boredom; contrasting colors for depth and drama; play up the wonderful architectural elements already found in the room; personalize it with what you love; and still, keep it simple and beautiful. Use soft lighting.

Good luck!